A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10068
Swiss-prot Accession numberQ8JIM3 (Sequence in FASTA format)
DescriptionGrowth hormone-releasing peptides precursor [Contains: Growth hormone-releasing peptide (GH-releasing peptide) (fGRP); fGRP-related peptide1; fGRP-related peptide 2; fGRP-related peptide 3].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the FARP (FMRFamide related peptide) family.
Tissue SpecificityObserved in the suprachiasmatic nucleus and in several telencephalic and diencephalic regions
Post translational modificationN/A
FunctionPrimary role is to release GH from the pituitary. May act as an endogenous ligand in the bullfrog hypothalamo-hypophysial system
Protein Length221 Amino acids
Molecular weight25886
References1  PubMed abstract 12208659
2  PubMed abstract 11796493
Domain NameN/A
Hormone NameGrowth hormone-releasing peptide
Mature Hormone SequenceSLKPAANLPLRF
Position of mature hormone in Pre-Hormone protein12 Residues from position (96-107)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10209
Swiss-prot Accession numberQ9PS36 (Sequence in FASTA format)
DescriptionFollitropin subunit beta (Follicle-stimulating hormone beta subunit)(FSH-beta) (FSH-B) (Follitropin beta chain).
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionStimulates development of follicle and spermatogenesis in the reproductive organs
Protein Length107 Amino acids
Molecular weight11794
References1  PubMed abstract 1426958
2  PubMed abstract 1426958
Domain NameCys_knot  
Hormone NameFollicle-stimulating hormone beta subunit
Mature Hormone SequenceCELSNITIVLEKEECGACVSVNATWCSGYCYTKDANLMYPQKSEKQGVCTYTEVIYETVKIPGCAENVNPFYTYPVAVDCHCGRCDSETTDCTVRALGPTYCSLSQD
Position of mature hormone in Pre-Hormone protein107 Residues from position (1-107)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10340
Swiss-prot Accession numberQ90Y63 (Sequence in FASTA format)
DescriptionProgonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (LHRH I) (Luteinizing hormone-releasing hormone I) (Gonadotropin-releasing hormone I) (GnRH I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)(GAP1)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted protein
Developmental StageExpressed at significantly higher levels during post-breeding. Not expressed in pituitary.
Similarity Belongs to the GnRH family.
Tissue SpecificityForebrain
Post translational modificationN/A
FunctionStimulates the secretion of gonadotropins
Protein Length90 Amino acids
Molecular weight10291
References1  PubMed abstract 11170016
Domain NameN/A
Hormone NameGonadoliberin-1
Mature Hormone SequenceQHWSYGLRPG
Position of mature hormone in Pre-Hormone protein10 Residues from position (25-34)
ReceptorQ9DE60   Detail in HMRbase   
Q9DE62   Detail in HMRbase   
Q9DE63    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments


Search Result - 4

HMRbase accession number10628
Swiss-prot Accession numberP80051 (Sequence in FASTA format)
DescriptionGlycoprotein hormones alpha chain (Anterior pituitary glycoproteinhormones common subunit alpha) (Follitropin alpha chain) (Follicle-stimulating hormone alpha chain) (FSH-alpha) (Lutropin alpha chain)(Luteinizing hormone alpha chain) (LSH-alpha) (Thyrotropin alphachain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha).
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit alpha family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionN/A
Protein Length97 Amino acids
Molecular weight11036
References1  PubMed abstract 1730225
2  PubMed abstract 1701134
Domain NameHormone_6  
Hormone NameGlycoprotein hormones alpha chain
Mature Hormone SequenceFPDDNFLTPGCPECRLKENLRFSNMGIGRIYQCSGCCYSRAYPTPMRSKKTMLVPKNITSEAKCCVAKTQYRVTVMDNVKIENHTACHCSTCLYHKS
Position of mature hormone in Pre-Hormone protein97 Residues from position (1-97)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10644
Swiss-prot Accession numberP80071 (Sequence in FASTA format)
DescriptionLutropin subunit beta (Luteinizing hormone subunit beta) (LSH-beta)(LSH-B) (LH-B) (Lutropin beta chain).
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionN/A
Protein Length112 Amino acids
Molecular weight12676
References1  PubMed abstract 1555571
Domain NameCys_knot  
Hormone NameLuteinizing hormone subunit beta (LSH-B) (LH-B)(Lutropin subunit beta)
Mature Hormone SequenceRHVCHLANATISAEKDHCPVCITFTTSICTGYCQTMDPVYKTALSSFKQNICTYKEIRYDTIKLPDCLPGTDPFFTYPVALSCYCDLCKMDYSDCTVESSEPDVCMKRRISI
Position of mature hormone in Pre-Hormone protein112 Residues from position (1-112)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number10690
Swiss-prot Accession numberP15427 (Sequence in FASTA format)
DescriptionPancreatic hormone (Pancreatic polypeptide) (PP).
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the NPY family.
Tissue SpecificityN/A
Post translational modification N/A
Function Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions
Protein Length36 Amino acids
Molecular weight4225
References1  PubMed abstract 3260236
Domain NameHormone_3  
Hormone NamePancreatic hormone
Mature Hormone SequenceAPSEPHHPGDQATPDQLAQYYSDLYQYITFITRPRF
Position of mature hormone in Pre-Hormone protein36 Residues from position (1-36)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10762
Swiss-prot Accession numberP10813 (Sequence in FASTA format)
DescriptionSomatotropin precursor (Growth hormone).
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted protein
Developmental StageLevels increase as metamorphosis progresses, reach maxima in juveniles and decrease as adulthood approaches.
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGrowth hormone plays an important role in growth control
Protein Length215 Amino acids
Molecular weight24975
References1  PubMed abstract 3260110
2  PubMed abstract 1476615
3  PubMed abstract 1859828
Domain NameHormone_1  
Hormone NameSomatotropin
Mature Hormone SequenceFPQMSLSNLFTNAVIRAQHLHQMVADTYRDYERTYIPEDQRFSNKHSYSVYCYSETIPAPTDKDNTHQKSDIDLLRFSLTLLQSWMTPIQIVNRVFGNNQVFGNIDRVYDRLRDLDEGLHILIRELDDGNVRNYGVLTFTYDKFDVNLRSEEGRAKNYGLLSCFKKDMHKVETYLKVMKCRRFVESNCTF
Position of mature hormone in Pre-Hormone protein190 Residues from position (26-215)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number10951
Swiss-prot Accession numberP11885 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length263 Amino acids
Molecular weight30389
References1  PubMed abstract 2788269
2  PubMed abstract 1331997
3  PubMed abstract 2788269
4  PubMed abstract 1331997
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMelanotropin gamma (Gamma-MSH)
Mature Hormone SequenceYVMSHFRWNKF
Position of mature hormone in Pre-Hormone protein11 Residues from position (77-87)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number10952
Swiss-prot Accession numberP11885 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length263 Amino acids
Molecular weight30389
References1  PubMed abstract 2788269
2  PubMed abstract 1331997
3  PubMed abstract 2788269
4  PubMed abstract 1331997
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameCorticotropin
Mature Hormone SequenceSYSMEHFRWGKPVGKKRRPIKVFPTDAEEESSESFPIEL
Position of mature hormone in Pre-Hormone protein39 Residues from position (144-182)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 10

HMRbase accession number10953
Swiss-prot Accession numberP11885 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length263 Amino acids
Molecular weight30389
References1  PubMed abstract 2788269
2  PubMed abstract 1331997
3  PubMed abstract 2788269
4  PubMed abstract 1331997
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMelanotropin alpha (Alpha-MSH)
Mature Hormone SequenceSYSMEHFRWGKPV
Position of mature hormone in Pre-Hormone protein13 Residues from position (144-156)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 11

HMRbase accession number10954
Swiss-prot Accession numberP11885 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length263 Amino acids
Molecular weight30389
References1  PubMed abstract 2788269
2  PubMed abstract 1331997
3  PubMed abstract 2788269
4  PubMed abstract 1331997
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameLipotropin beta (Beta-LPH)
Mature Hormone SequenceELSLEFDYPDTNSEEELDNGELLEGPVKKGRKYKMHHFRWEGPPKDKRYGGFMTPERSQTPLMTLFKNAIIKNAHKKGQ
Position of mature hormone in Pre-Hormone protein79 Residues from position (185-263)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 12

HMRbase accession number10955
Swiss-prot Accession numberP11885 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length263 Amino acids
Molecular weight30389
References1  PubMed abstract 2788269
2  PubMed abstract 1331997
3  PubMed abstract 2788269
4  PubMed abstract 1331997
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameLipotropin gamma (Gamma-LPH)
Mature Hormone SequenceELSLEFDYPDTNSEEELDNGELLEGPVKKGRKYKMHHFRWEGPPKD
Position of mature hormone in Pre-Hormone protein46 Residues from position (185-230)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 13

HMRbase accession number10956
Swiss-prot Accession numberP11885 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length263 Amino acids
Molecular weight30389
References1  PubMed abstract 2788269
2  PubMed abstract 1331997
3  PubMed abstract 2788269
4  PubMed abstract 1331997
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMelanotropin beta (Beta-MSH)
Mature Hormone SequenceGRKYKMHHFRWEGPPKD
Position of mature hormone in Pre-Hormone protein17 Residues from position (214-230)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 14

HMRbase accession number10957
Swiss-prot Accession numberP11885 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length263 Amino acids
Molecular weight30389
References1  PubMed abstract 2788269
2  PubMed abstract 1331997
3  PubMed abstract 2788269
4  PubMed abstract 1331997
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameBeta-endorphin
Mature Hormone SequenceYGGFMTPERSQTPLMTLFKNAIIKNAHKKGQ
Position of mature hormone in Pre-Hormone protein31 Residues from position (233-263)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 15

HMRbase accession number10958
Swiss-prot Accession numberP11885 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length263 Amino acids
Molecular weight30389
References1  PubMed abstract 2788269
2  PubMed abstract 1331997
3  PubMed abstract 2788269
4  PubMed abstract 1331997
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMet-enkephalin
Mature Hormone SequenceYGGFM
Position of mature hormone in Pre-Hormone protein5 Residues from position (233-237)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 16

HMRbase accession number11119
Swiss-prot Accession numberP15438 (Sequence in FASTA format)
DescriptionGlucagon precursor [Contains: Glucagon; Glucagon-36 (Oxyntomodulin);Glucagon-like peptide 1; Glucagon-like peptide 2] (Fragments).
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the glucagon family.
Tissue SpecificityN/A
Post translational modification N/A
Function Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level
Protein Length103 Amino acids
Molecular weight11721
References1  PubMed abstract 3260236
Domain NameHormone_2  
Hormone NameGlucagon-36
Mature Hormone SequenceHSQGTFTSDYSKYLDSRRAQDFVQWLMNSKRSGGIS
Position of mature hormone in Pre-Hormone protein36 Residues from position (1-36)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 17

HMRbase accession number11120
Swiss-prot Accession numberP15438 (Sequence in FASTA format)
DescriptionGlucagon precursor [Contains: Glucagon; Glucagon-36 (Oxyntomodulin);Glucagon-like peptide 1; Glucagon-like peptide 2] (Fragments).
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the glucagon family.
Tissue SpecificityN/A
Post translational modification N/A
Function Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level
Protein Length103 Amino acids
Molecular weight11721
References1  PubMed abstract 3260236
Domain NameHormone_2  
Hormone NameGlucagon
Mature Hormone SequenceHSQGTFTSDYSKYLDSRRAQDFVQWLMNS
Position of mature hormone in Pre-Hormone protein29 Residues from position (1-29)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 18

HMRbase accession number11121
Swiss-prot Accession numberP15438 (Sequence in FASTA format)
DescriptionGlucagon precursor [Contains: Glucagon; Glucagon-36 (Oxyntomodulin);Glucagon-like peptide 1; Glucagon-like peptide 2] (Fragments).
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the glucagon family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionN/A
Protein Length103 Amino acids
Molecular weight11721
References1  PubMed abstract 3260236
Domain NameHormone_2  
Hormone NameGlucagon-like peptide 1
Mature Hormone SequenceHADGTFTSDMSSYLEEKAAKEFVDWLIKGRPK
Position of mature hormone in Pre-Hormone protein32 Residues from position (39-70)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 19

HMRbase accession number11122
Swiss-prot Accession numberP15438 (Sequence in FASTA format)
DescriptionGlucagon precursor [Contains: Glucagon; Glucagon-36 (Oxyntomodulin);Glucagon-like peptide 1; Glucagon-like peptide 2] (Fragments).
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the glucagon family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionN/A
Protein Length103 Amino acids
Molecular weight11721
References1  PubMed abstract 3260236
Domain NameHormone_2  
Hormone NameGlucagon-like peptide 2
Mature Hormone SequenceHADGSFTSDFNKALDIKAAQEFLDWIINTPVKE
Position of mature hormone in Pre-Hormone protein33 Residues from position (71-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 20

HMRbase accession number11189
Swiss-prot Accession numberP80344 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 33 (CCK33); Cholecystokinin 8 (CCK8);Cholecystokinin 7 (CCK7)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, lung, testis and throughout the length of the small intestine. In the brain, expressed predominantly in the optic tectum and brain stem
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14449
References1  PubMed abstract 9075736
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQQTVGSMNEDPGAREIEQQNILQHPRHIRASSSAQLKPFQRIDGTSDQKAVIGAMLAKYLQTRKAGSSTGRYAVLPNRPVIDPTHRINDRDYMGWMDFGRRSAEEYEYSS
Position of mature hormone in Pre-Hormone protein110 Residues from position (21-130)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 21

HMRbase accession number11190
Swiss-prot Accession numberP80344 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 33 (CCK33); Cholecystokinin 8 (CCK8);Cholecystokinin 7 (CCK7)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, lung, testis and throughout the length of the small intestine. In the brain, expressed predominantly in the optic tectum and brain stem
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14449
References1  PubMed abstract 9075736
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-58
Mature Hormone SequenceRIDGTSDQKAVIGAMLAKYLQTRKAGSSTGRYAVLPNRPVIDPTHRINDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein58 Residues from position (61-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 22

HMRbase accession number11191
Swiss-prot Accession numberP80344 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 33 (CCK33); Cholecystokinin 8 (CCK8);Cholecystokinin 7 (CCK7)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, lung, testis and throughout the length of the small intestine. In the brain, expressed predominantly in the optic tectum and brain stem
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14449
References1  PubMed abstract 9075736
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-33
Mature Hormone SequenceGSSTGRYAVLPNRPVIDPTHRINDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein33 Residues from position (86-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 23

HMRbase accession number11192
Swiss-prot Accession numberP80344 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 33 (CCK33); Cholecystokinin 8 (CCK8);Cholecystokinin 7 (CCK7)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, lung, testis and throughout the length of the small intestine. In the brain, expressed predominantly in the optic tectum and brain stem
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14449
References1  PubMed abstract 9075736
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (111-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 24

HMRbase accession number11193
Swiss-prot Accession numberP80344 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 33 (CCK33); Cholecystokinin 8 (CCK8);Cholecystokinin 7 (CCK7)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, lung, testis and throughout the length of the small intestine. In the brain, expressed predominantly in the optic tectum and brain stem
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14449
References1  PubMed abstract 9075736
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-7
Mature Hormone SequenceYMGWMDF
Position of mature hormone in Pre-Hormone protein7 Residues from position (112-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 25

HMRbase accession number11398
Swiss-prot Accession numberP0C234 (Sequence in FASTA format)
DescriptionCalcitonin.
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the calcitonin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionCauses a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones
Protein Length32 Amino acids
Molecular weight3426
References1  PubMed abstract 9245522
Domain NameCalc_CGRP_IAPP  
Hormone NameCalcitonin
Mature Hormone SequenceCSGLSTCALMKLSQDLHRFNSYPRTNVGAGTP
Position of mature hormone in Pre-Hormone protein32 Residues from position (1-32)
ReceptorQ7SX84    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments


Search Result - 26

HMRbase accession number11508
Swiss-prot Accession numberQ9DG36 (Sequence in FASTA format)
DescriptionProgonadoliberin-2 precursor (Progonadoliberin II) [Contains:Gonadoliberin-2 (Gonadoliberin II) (LHRH II) (Luteinizing hormone-releasing hormone II) (Gonadotropin-releasing hormone II) (GnRH II)(Luliberin II); GnRH-associated peptide 2 (GnRH-associated peptide II)(GAP2)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted protein
Developmental StageExpressed at significantly higher levels during hibernation and post-breeding. Not expressed in pituitary.
Similarity Belongs to the GnRH family.
Tissue SpecificityMidbrain and hindbrain
Post translational modificationN/A
Function Stimulates the secretion of gonadotropins
Protein Length93 Amino acids
Molecular weight10668
References1  PubMed abstract 11170016
Domain NameN/A
Hormone NameGonadoliberin-2
Mature Hormone SequenceQHWSHGWYPG
Position of mature hormone in Pre-Hormone protein10 Residues from position (25-34)
ReceptorQ9DE60   Detail in HMRbase   
Q9DE62   Detail in HMRbase   
Q9DE63    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments